This one isn't looking good for the Titans.  The only thing that the Titans have going for them is the fact that the Colts have an injury list almost as long as the Redskins.  Tennessee does have the second best pass defense.  They should be able to hold Luck to under 300 yards, but at the same time, the Titans will need to score to make this one close.  Locker is questionable and far from 100%, which doesn't bode well for the Titans chances of pulling this one out.  The Colts are at home, they want to bring their record back to .500, and the Titans after this week should be a 1-3 team because they're just not that good.  I think the spread is almost a lock for the Colts to cover and though the Titans pass defense will keep Luck somewhat in check, he will ultimately win this battle.  The Titans are holding opposing passing offenses to 170 yards on average, but I would pretty much bet everything in the world that Andrew Luck surpasses that total.  I'm thinking around 260 yards in the air and 20+ points.  And I just don't think the Titans have the offense that can score 20 points right now, especially with Locker on the ropes.  Colts should win this one convincingly, but they better start stopping the pass.  This should be a good game for them to do well in that department.

COLTS 26 - TITANS 13

FANTASY BEAST: COLTS DEFENSE